You will need a dedicated column for each type of information in your spreadsheet. Upon import, these data columns have to be included in the node list data range. yEd will then import said data as custom properties. Using an appropriate properties mapper configuration, it is possible to apply the data in the custom properties to e.g. labels of your nodes. If you prepare such a properties mapper configuration beforehand, yEd's Excel Import offers the option to automatically map the data/properties on import (see tab "Presentation", section "Nodes", option "Use Configuration" in the Excel Import settings).